| Item Type | Name |
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Grant
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RISE Option II at Xavier University of Louisiana
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Grant
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Multi-Target, Mechanism-Based Drug Design for the Treatment of Breast Cancer: Syn
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Grant
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Ceramides for Breast Cancer Treatment
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Academic Article
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Novel D: -erythro N-octanoyl sphingosine analogs as chemo- and endocrine-resistant breast cancer therapeutics.
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Academic Article
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Novel anti-viability ceramide analogs: design, synthesis, and structure-activity relationship studies of substituted (S)-2-(benzylideneamino)-3-hydroxy-N-tetradecylpropanamides.
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Academic Article
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Development of flavone propargyl ethers as potent and selective inhibitors of cytochrome P450 enzymes 1A1 and 1A2.
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Academic Article
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DESIGN, SYNTHESIS, AND EVALUATION OF A FAMILY OF PROPARGYL PYRIDINYL ETHERS AS POTENTIAL CYTOCHROME P450 INHIBITORS.
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Academic Article
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DESIGN, SYNTHESIS, AND EVALUATION OF CARBAZOLE ANALOGS AS POTENTIAL CYTOCHROME P450 INHIBITORS.
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Academic Article
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3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.
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Academic Article
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A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
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Academic Article
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Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1).
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Academic Article
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Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme.
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Academic Article
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Inhibition of breast tumor growth in mice after treatment with ceramide analog 315.
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Academic Article
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DESIGN AND SYNTHESIS OF DIBENZYLFURAN BASED ETHER AND ESTER DERIVATIVES AS POTENTIAL P450 INHIBITORS.
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Academic Article
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Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
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Academic Article
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Differential inhibition of cytochromes P450 3A4 and 3A5 by the newly synthesized coumarin derivatives 7-coumarin propargyl ether and 7-(4-trifluoromethyl)coumarin propargyl ether.
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Concept
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Adamantane
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Concept
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Alkynes
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Concept
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Anthraquinones
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Concept
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Antineoplastic Agents
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Concept
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Antitubercular Agents
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Concept
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Aryl Hydrocarbon Hydroxylases
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Concept
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Binding Sites
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Concept
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Biphenyl Compounds
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Concept
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Carbazoles
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Concept
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Carcinogens
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Concept
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Ceramides
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Concept
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Coumarins
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Concept
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Cytochrome P-450 Enzyme System
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Concept
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Dimethyl Sulfoxide
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Concept
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Dioxanes
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Concept
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Dose-Response Relationship, Drug
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Concept
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Environmental Pollutants
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Concept
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Enzyme Inhibitors
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Concept
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Ethers
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Concept
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Flavonoids
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Concept
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Glucosyltransferases
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Concept
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Hormones
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Concept
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Hydrocarbons, Aromatic
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Concept
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Hydrocortisone
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Concept
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Imidazoles
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Concept
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Indoles
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Concept
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Ketones
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Concept
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Lactones
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Concept
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Ligands
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Concept
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Lysophospholipids
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Concept
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NADP
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Concept
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Naphthalenes
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Concept
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Nicotine
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Concept
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Phenanthrenes
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Concept
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Phenylalanine
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Concept
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Polycyclic Compounds
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Concept
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Pyrenes
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Concept
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Pyridines
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Concept
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Quinones
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Concept
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Sesquiterpenes
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Concept
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Sphingolipids
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Concept
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Sphingosine
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Concept
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Steroid 11-beta-Hydroxylase
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Concept
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Steroid 17-alpha-Hydroxylase
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Concept
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Steroid 21-Hydroxylase
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Concept
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Stilbenes
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Concept
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Tryptophan
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Concept
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Drug Design
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Concept
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Xenobiotics
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Concept
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Apoptosis
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Concept
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Phosphotransferases (Alcohol Group Acceptor)
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Concept
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Receptors, Aryl Hydrocarbon
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Concept
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Cell Cycle Proteins
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Concept
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Drug Resistance, Neoplasm
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Concept
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Cytochrome P-450 CYP1A1
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Concept
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Cytochrome P-450 CYP1A2
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Concept
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Ki-67 Antigen
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Concept
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Chlorodiphenyl (54% Chlorine)
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Concept
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Benzeneacetamides
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Concept
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Flavones
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Concept
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Protein Kinase Inhibitors
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Concept
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Cytochrome P-450 CYP3A
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Concept
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Small Molecule Libraries
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Concept
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Ceramidases
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Academic Article
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Anti-cancer effectiveness of a novel ceramide analog on chemo-sensitive and chemo-resistant breast cancers.
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Academic Article
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Design, Synthesis, and Biological Studies of Flavone-Based Esters and Acids as Potential P450 2A6 Inhibitors.
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